Associated TP20: Effect of differentially glycosylated antibodies on autoantigen-specific B cells
The pro- or anti-inflammatory effector function of an antibody depends on its Fc N-glycosylation (e.g. J Clin Invest. 2013; J Allergy Clin Immunol. 2012). Regarding findings in J Exp Med. 2006 we will investigate which glycosylation of different murine and human IgG subclasses have an inhibiting effect on autoantigen specific B cells in vitro and in vivo. Furthermore we would like to characterize the inhibiting receptor involved.
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- associated TP1 - Immunoadsorbtion
- associated TP2 - Breg
- associated TP3 - Osteoimmunology
- associated TP4 - Cytokines in EBA
- associated TP5 - Scaring alopecia
- associated TP6 - Diet and Autoimmunity
- associated TP7 - QTL in RA
- associated TP8 - Systems biology
- associated TP9 - Microbiome
- associated TP10 - Wound healing in EBA
- associated TP11 - Novel BP model
- associated TP12 - Anti-p200 pemphigoid
- associated TP13 - miRNA expression patterns
- associated TP14 - therapeutic Collagen VII and XVII-specific IgGs
- associated TP 15 - Bioactive lipid mediaters
- associated TP 17 - The role of mitochondrial DNA
- associated TP 18 -Pathogenesis of pemphigoid diseases
- associated TP 19 - New neutrophil inhibitors
- associated TP 20 - Glycosylated antibodies & autoreactive B cells
- associated TP 21 - Glycosylated IgA
- associated TP 22 - Neuronal auto-antigens
- associated TP 23 - Neuroinflammatory autoantibodies
- associated TP 24 - T cell repertoire
- associated TP 25 - Nutrition in EBA
- associated TP 26 - Circadian clocks in EBA
- associated TP 27 - Pemphigus characterization
- associated TP 28 - Mast cells in BP
- associated TP 29 - IL-10 in EBA
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