MD TP21: Influence of NF-κB on the pathogenesis of EBA
Previous studies could show that antibodies from autoimmune bullous diseases induce an altered cytokine liberation in keratinocytes.
By stimulating cultured human keratinocytes with antibodies from patients with Epidermolysis bullosa acquisita (EBA), we want to investigate the impact of NF-κB on the release of mediators by these cells, and further want to elucidate intra- and extracellular pathways leading to NF-κB activation by EBA antibodies.
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- Concluded TP
- Concluded Ass.TP
- Concluded MD TP
- MD TP1 - Ig Glycolysation
- MD TP2 - Immunoprivilege
- MD TP3 - ANA antibodies
- MD TP4 - Autoantibody prevalence
- MD TP5 - Treatment of EBA
- MD TP6 - Autoantibody-induced tissue injury
- MD TP7 - Neutrophil signalling
- MD TP7b - IgG-IC-induced signalling
- MD TP8 - The role of IL-33 and its receptor ST2
- MD TP9 - Detection of antigen-specific B cells
- MD TP9b - Detection of antigen-specific B cells in BP
- MD TP10 - Old drugs to block T cells
- MD TP10b - Combination of T cell inhibitory compounds
- MD TP10c - T cell inhibitory compounds (in vivo)
- MD TP11 - Identification of "genetic biomarkers"
- MD TP12 - Combinations of B cell modulatory compounds
- MD TP13 - TREM1 in cutaneous inflammation
- MD TP14 - Signaling in PV
- MD TP15 - Autoantibodies in relatives
- MD TP16 - Drug-induced pemphigoid
- MD TP17 - Keratinocyte lipid mediators
- MD TP18 - Neutrophils + IL-17A-Inhibition
- MD TP19 - C5aR-Inhibition
- MD TP20 - IgG-Subclasses
- MD TP21 - NF-kB in EBA
- MD TP22 - Biochip Mosaics in AIBD
- MD TP23 - Diagnostic Techniques on AIBD
- MD TP24 - Anti-stimulatory effects on Neutrophil-signaling
- MD TP25 - Phage library on systemic scleroderma
- MD TP26 - New EBA-scoring sytem
- MD TP27 - Neutrophil signaling-pathway inhibition
- MD TP28 - Inhibition of Keratinocytes
- MD TP29 - Monoclonal antibodies in EBA
- MD TP30 - Enhancing vaccinations under Immunosuppression
- MD TP31 - Non-desmoglein autoantibodies in PV
- MD TP32 - Neutrophil adhesion
- MD TP33 - MicroRNA-21 in BP
- MD TP34 - PI3K-subunits in EBA
- MD TP35 - Signaling cascade inhibition in EBA
- MD TP36 - Signaling cascades in keratinocytes
- MD TP37 - AT1R-antibodies
- MD TP38 - Cell migration regulation
- MD TP39 - mACh-Receptors in systemic sclerosis
- MD TP40 - Hair and EBA
- MD TP41 - CMV-specific T cells
- MD TP42 - Necroptosis in GPA
- MD TP43 - Neutrophils and NETs
- MD TP44 - Mitochondrial genome in AIBD
- MD TP45 - Target antigens in pemphgoid diseases
- MD TP46 - Alpha-adrenoceptors in Raynaud´s phenomenon
- MD TP47 - T cell-receptor-sequences in autoimmune skin diseases
- MD TP48 - Epitope specificity and glycolization
- MD TP49 - Inhibition of keratinocyte-dissociation
- MD TP50 - Transcriptome profile of endothelial cells induced by autoantibodies targeting AT1R/ETAR in systemic sclerosis
- MD TP52 - Expression of B4GALT1 and ST6GAL1 ....
- MD TP54 - Reactivity of serum antibodies ....
- MD TP55 - Identification of potential therapeutics .....
- MD TP56 - Validation of the inhibition of different signalling pathways ...
- MD TP57 - Inhibition of IFN-γ as therapy for epidermolysis bullosa acquisita
- MD TP58 - Characterization of immunoglobulin G subclass distribution ...
- MD TP59 - Development of an experimental pemphigus vulgaris model in adult mice
- MD TP60 - Interactions between GPCR and anti-GPCR IgG autoantibodies...
- MD TP61 - Glycosyltransferases B4GALT1 and ST6GAL1 in...
- MD TP62 - Sensitivity of diagnostic test systems in dermatitis herpetiformis Duhring
- Concluded Ass. MD TP