The reported prevalence of antinuclear antibodies (ANA) in healthy populations ranges from 5% to 30%. This difference may be due to the relative small sample sizes and different test systems used. We here will determine the incidence of ANA in a cohort of over 10,000 blood donors using immunofluorescence testing. 

Parts of the thesis have been published (Prüßmann & Prüßmann et al, Exp Dermatol). Jaspar Prüßmann received his Dr. med. degree in 06/2015 and ist currently working as a PostDoc in the AG Mempel at the Department of Pathology of the Harvard University in Boston.